This intricate process allows bile acids to function beyond digestion as metabolic regulators. However, disruptions in this circuit can lead to gastrointestinal diseases, making bile acids a critical ...

How did you discover MCBAs? Bile acids were first described chemically in 1849, and Heinrich Wieland was awarded a Nobel Prize in 1927 for comprehensively describing their chemistry. This ...

Bile reflux gastritis (BRG) is a gastro-intestinal condition especially characterized by the reflux of bile into the stomach, further leading to mucosal inflammation along with various other clinical ...

"Some microbial bile acids support FXR's function, while others antagonize it," says Ting Fu, an assistant professor in the UW–Madison School of Pharmacy. Fu and her colleagues previously ...

Scientists have identified new ways in which bile acids interact with cellular stress responses, impacting how the liver ...