Mahta Barekatain, PhD, from the University of Southern California, and collaborators used mass spectrometry, mutagenesis, and ...
Recent advances in automated protein design algorithms are leading a resurgence in structure-based design approaches ... of the Streptococcal protein G ß1 domain. We have only just begun to ...
At right: A ribbon diagram of the G protein structure shows the position of all phosphoevents the “buzzer” site in red.
"The key to understanding this family of proteins has been the determination of their molecular structure. "Now, half of all medications achieve their effect through G-protein-coupled receptors. It is ...
The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...