One such gene encodes GDNF, a growth factor that promotes survival ... A key occurrence in AMD is the progressive loss of the retinal pigment epithelium, a single layer of cells that protects ...

GDNF has been hailed as a potential breakthrough for Parkinson’s ever since it was discovered in 1993. In the lab, it was shown to bring dying brain cells back to life and it has proved to be ...

Using a combination of rational drug design methods and a set of biological assays, we identified three scaffolds of chemical compounds specifically targeting the receptors of glial cell line-derived ...

The Glial cell line-Derived Neurotrophic Factor (GDNF) was originally found when searching for a neurotrophic factor which would prevent the continued degeneration of midbrain dopaminergic neurons—a ...