A new study helps explain the role of genetic variation in shaping gene regulation in the Indonesian archipelago, one of the most diverse regions in the world. “This study is the only study of ...

Alternative splicing plays a pivotal role in defining cell phenotypes and physiology in multicellular eukaryotes, often distinguishing between cell types more accurately than gene expression. 1 During ...

The study focused on splicing – one of the key levels of control in the gene expression process. Splicing, as the name suggests, is a process by which molecular machines in the cell 'cut and paste' ...

Exciting results for MeiraGTx Holdings plc's GAD gene therapy for Parkinson's Disease, with promising phase 1/2 data and ...

He identified a new aging-associated gene known as Splicing factor proline—and glutamine-rich or Sfpq, which is involved in the ribonucleic acid (RNA) transcription of long genes. Later ...

Frontotemporal dementia (FTD) often strikes our most human traits, such as the ability to speak and to interact on social and emotional levels. Now, research led by Lorenzo Pasquini and William Seeley ...

A study published in Molecular Psychiatry is the first to suggest that the use of high-potency cannabis leaves a distinct mark on DNA, providing valuable insights into the biological impact of ...

Sep. 25, 2024 — Adults with hemophilia B saw their number of bleeding episodes drop by an average of 71 percent after a single infusion of gene therapy, according to the new results of an ...

Gene therapy with elivaldogene autotemcel (eli ... related to lentiviral vector insertions associated with abnormal splicing events. 12,13 We comprehensively characterize the clinicopathological ...

Researchers at the University of Toronto have shown that an important class of DNA-binding factors can also bind to RNA, ...

To better understand the potential impacts, Kappert and colleagues used gene editing to generate a Ptprj knockout cell model in the murine neuroblast cell line Neuro2a. They found that Ptprj ...

ARTHEx Biotech S.L., a clinical-stage biotechnology company focused on developing innovative medicines through the modulation of gene expression, announced today that the first participant has been ...