Purpose: Approximately 20% of patients with congenital absence of the vas deferens remain without two mutations identified. We applied a strategy of serial screening steps to 45 patients with ...

The CFTR Rat Models Core was established in 2018 in response to the need demonstrated by the CF community for support in the distribution and utilization of CF rats. Specifically, the Core is designed ...

It provides a completely novel approach to treating the cause and symptoms of cystic fibrosis (CF)-associated respiratory infections in all CF patients, regardless of CFTR genotype/ mutation status.

The CFTR Protein Distribution Core offers high-quality, full-length recombinant cystic fibrosis transmembrane conductance regulator (CFTR) proteins expressed in and purified from mammalian cells. Wild ...