To Jubao Duan of the University of Chicago, the authors provide compelling evidence. That tau dysregulation derails lipid droplets “provides novel mechanistic insight into how accumulation of human ...

Glial cells come in many forms, but three major types are currently recognized: astrocytes, oligodendrocytes and microglia. The first are primarily involved in creating the blood-brain barrier and ...

With ageing, glial cells become more and more primed and ready to over respond as the years go by – Linda Watkins Microglia could play an important role in chronic pain too, defined as pain that ...

Deletion of the ‘glial cells missing-2’ gene in mice disrupts development of the parathyroid glands but does not eliminate production of parathyroid hormone (PTH), which is required for ...

Breast cancer cells send microRNA-filled vesicles to the brain, creating a nutrient-rich environment that facilitates ...

Microglia are the brain's resident immune cells. Their job is to patrol the brain's blood vessels looking for invading ...

Diminishing energy production in aging neurons triggers senescence in nearby glial cells, which ordinarily support and protect neurons. With age, some cells in the brain enter a state of senescence: ...

Our laboratory sits at the interface between stem cell biology and developmental neuroscience. We use pluripotent stem cells to model neurological development and disease with a specific focus on ...

Prior research has shown that numerous brain cells called astrocytes appear to play a role in providing the brain neurons with energy they need. Astrocytes, shaped like stars, are a type of glial cell ...

It was published in the September Nature. “Alzheimer’s is not a single-cell disease, but a disease of the whole brain environment,” De Jager told Alzforum. Single-nucleus RNA-Seq spots three glial ...

Michael Barresi’s research interests are focused on how glial cells help wire the nervous system in the embryonic zebrafish brain. His lab discovered that astroglial cells provide a substrate for ...