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The amyloid cascade—plaques to tangles to cognitive decline—has become well established. Less well understood is what role inflammation and glial changes play. Now, by analyzing single-nuclei RNA-Seq ...

Breast cancer cells send microRNA-filled vesicles to the brain, creating a nutrient-rich environment that facilitates ...

“It differs significantly from other tissue clearing methods, which break down the lipid membranes, and therefore compromise the structure of the tissue.” As a gentler method for rendering ...

Currently, a definite diagnosis of glioblastoma multiforme (GBM) can be made only by the histopathological analysis of tumor tissue. Glial fibrillary acidic protein (GFAP) is a marker of ...

Definitive diagnosis of glioma requires a biopsy and pathology, including histology and molecular testing. A tissue biopsy ...

More information: Daniel Bormann et al, Single-nucleus RNA sequencing reveals glial cell type-specific responses to ischemic ...

A glioma is a type of tumor that originates in the central nervous system, specifically in the brain or spinal cord. These tumors originate in glial cells, supportive cells in the brain which serve to ...

Michael Barresi’s research interests are focused on how glial cells help wire the nervous system in the embryonic zebrafish ... Additionally, zebrafish embryos are optically transparent, enabling the ...

"Our description of the interaction between immune and glial cells in the infarct area contributes considerably to a better ...

Calcineurin fine tunes the balance between proliferation and differentiation of Notch-responsive progenitors in the pancreatic ducts to enable beta cell regeneration in zebrafish.

The study is a valuable addition to the field, showing how particulate matter may be acting via nociceptor neurons towards neutrophilic asthma exacerbations. The solid evidence for the role of a ...