Hosted on MSN10mon
Protein-glutaminase creates juicier, more digestible meat-free burgers
This new approach employed protein-glutaminase treatment to improve digestibility and make the burger juicier. According to the study, researchers aimed to improve the juiciness of plant-based meat ...
The American Journal of Managed Care3d
Phase 1b/2 Study Supports Use of Telaglenastat and Azacytidine in Advanced MDS
A recent study evaluates the dosing, safety, and efficacy of telaglenastat and azacytidine to treat advanced myelodysplastic ...
EurekAlert!24d
Strategy to combat breast cancer involves two-pronged attack on enzyme that ‘feeds’ tumor
A study led by Brazilian researchers and reported in an article published in the journal Nature Communications proposes that simultaneously targeting the enzyme glutaminase and the protein HuR ...
Nature25d
Oncology articles from across Nature Portfolio
In patients with MDS, malignant cells rely on glutamine for survival and exhibit elevated levels of glutaminase, an essential enzyme for glutamine metabolism. Our results from preclinical and ...
Medical Xpress25d
Strategy to combat breast cancer involves two-pronged attack on enzyme that 'feeds' tumor
Isoforms The findings show that HuR, which is often overexpressed in cancer patients, plays a vital role in ensuring that the right isoform of glutaminase is produced. "When levels of HuR are low ...
Hosted on MSN24d
Strategy to combat breast cancer involves two-pronged attack on enzyme that 'feeds' tumor
More information: Douglas Adamoski et al, HuR controls glutaminase RNA metabolism, Nature Communications (2024). DOI: 10.1038/s41467-024-49874-x Provided by FAPESP ...