Cell-to-cell communication through nanosized particles, working as messengers and carriers, can now be analyzed in a whole ...

The genome-editing technology can be supercharged by artificial intelligence—and the results are already being felt.

The United States Food and Drug Administration has just approved the first-ever clinical trial that uses CRISPR-Cas13 RNA ...

This protein can easily be programmed to find and bind to almost any desired target sequence, simply by giving it a piece of RNA to guide it in its search. When the CRISPR Cas9 protein is added to ...

All DNA-binding CRISPR-Cas systems use this structure to ... the presence of a DNA sequence that sufficiently matches the guide RNA. The R-loop essentially tells the system when it's appropriate ...

CRISPR-Cas9 has long been likened to a kind ... cell as long as the target transcript that's been recognized by the guide RNA ...

Yao. The success of RNA-targeting CRISPR tools depends on multiple factors, including the guide RNA sequence, the ...

CRISPR-Cas9 is a reprogrammable DNA cutting ... any sequence along the genome--by hitching it to a strand of guide RNA (green) whose sequence is complementary to that of the DNA target.

RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA ... Jan. 13, 2024 — To combat viruses, bacteria and other pathogens, synthetic ...

With CRISPR-Cas9, the crRNA/tracrRNA sequence or an artificial guide RNA indicate where the DNA can be cut. It is relatively easy for scientists to produce different sequence variants from RNA ...