CRISPR technology, driven by Cas9, redefines gene editing, facilitating targeted DNA modifications that advance genetic ...

More information: Zitian Yang et al, CRISPRlnc: a machine learning method for lncRNA-specific single-guide RNA design of CRISPR/Cas9 system, Briefings in Bioinformatics (2024). DOI: 10.1093/bib ...

The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic diseases to antiviral therapies and diagnostics. However, to safely harness their powers, ...

This protein can easily be programmed to find and bind to almost any desired target sequence, simply by giving it a piece of RNA to guide it in its search. When the CRISPR Cas9 protein is added to ...

What are some CRISPR-based strategies for insect control that you have developed? We recently developed a new technology that uses CRISPR to block viral transmission. There are CRISPR ribonucleases ...

1 These systems consist of clustered, regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins. 1 CRISPR-Cas systems utilize RNA guides to direct Cas proteins ...

The team discovered that an RNA ... how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to ... Researchers Develop DANGER Analysis Tool for the Safer Design ...

With CRISPR-Cas9, the crRNA/tracrRNA sequence or an artificial guide RNA indicate where the DNA can be cut ... Meganucleases are an example of such unique sequences. The design of such enzymes that ...

One of bacterial cells' most well-known defenses against these viruses is the CRISPR system ... that sequence produces a guide RNA that directs an enzyme called Cas9 to snip the viral DNA ...

By Balambal Suryanarayanan CRISPR-Cas9 is a repurposed gene editing tool that allows scientists to cut, replace, and insert pieces of DNA in precise regions along the strand. Courtesy of NIH Image ...

RNA-based therapeutics have rapidly emerged over the past decade, offering a new class of medicines that differ significantly from conventional drugs. These therapies can be programmed to target or ...