T helper (TH) cells are essential immune cells that help other immune cells function effectively. When activated in response ...
Identifying this organelle as a potential target to improve the performance of T-cells in the TME, the team set out to ...
Gene expression is regulated by transcription factors in concert with epigenetic modifications (such as DNA methylation, post-translational histone modifications, the position and compaction of ...
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The mechanism mirrors how ICIs might trigger other immune-related events by enhancing T helper cell proinflammatory responses. According to the findings, loss of T-cell tolerance contributes to ...