Sickle cell hemoglobin (HbS) behaves like normal hemoglobin ... resulting in a chronic hemolytic anemia with red cell destruction, the rate of which is influenced by factors such as infection ...
Hemoglobin SS, also called sickle cell anemia, is usually the most severe type of this disorder. A blood test can check for the defective form of hemoglobin found in people with sickle cell disease.
At 9 months of age he appeared pale. Anemia was found, and electrophoresis established the diagnosis of sickle-cell disease. Both parents had hemoglobin-AS pattern on electrophoresis but were ...