Scientists discover new details of gene regulation that control cell identity
Genes make up the blueprints and outline the process of building every living organism. To ensure that the right genes are ...
EurekAlert!20d
The imbalance of homeostasis in neutrophil extracellular traps is associated with portal vein thrombosis in patients with decompensated cirrhosis
Plasma samples were assessed for NET markers, including cell-free DNA (cfDNA) and histone-DNA complexes, along with DNase activity. PVT patients exhibited elevated levels of cfDNA and histone-DNA ...
Nature2y
histone / histones
The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...
Nature2y
Examining Histone Modifications with Chromatin Immunoprecipitation and Quantitative PCR
How? Scientists are using ChIP and PCR to find out. To examine changes in histone modification during blood cell development in chickens, the investigators started with whole chromatin from ...
Medscape10d
Expression of Histone Deacetylases 1, 2 and 3 in Urothelial Bladder Cancer
This is the first comprehensive immunohistochemical analysis of the expression of several class I HDAC proteins (1, 2 and 3) in urothelial carcinoma. In our study, we found all three isoforms in a ...