GEN2d
Cholesterol Metabolite Implicated in Parkinson’s Disease Pathology
Researchers suggest drugs that prevent cholesterol from being converted to 24-OHC might therefore be an effective treatment for Parkinson's disease.
Nature19y
Neuronal Tryptophan Hydroxylase mRNA Expression in the Human Dorsal and Median Raphe Nuclei: Major Depression and Suicide
Tryptophan hydroxylase (TPH) is the rate-limiting biosynthetic enzyme for serotonin. Previously, we reported elevated levels of TPH protein in the dorsal raphe nucleus (DRN) of depressed suicides ...
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ACMG sets new lifelong guidelines for managing phenylalanine hydroxylase deficiency
Revolutionizing care for phenylalanine hydroxylase (PAH) deficiency, ACMG's updated guidelines highlight evidence-based strategies to enhance neurocognitive health and protect maternal and fetal ...