The function of human airway macrophages can be therapeutically manipulated by targeting cellular metabolism to support immunity in the lung, aiding the design of innovative strategies in respiratory ...

On the 50th anniversary of the discovery of interferon (IFN), we offer a perspective from more than 100,000 published papers, highlighting initial pivotal discoveries and more recent findings of ...

Figure 1: IFN-γ capture assay enriches tumor-reactive T cells from immunized mice. Figure 3: IFN-γ capture assay detects and enriches tumor-specific T cells from human RCC. In conclusion ...

Interferon gamma (IFN-γ) is a cytokine that induces a series of immune responses against viruses and tumors. The pro-apoptotic, anti-tumor and anti-proliferative actions of the cells are ...

EULAR - The European Alliance of Associations for Rheumatology - held its 2024 congress in Vienna, where new work was unveiled on the potential value of the blood interferon signature in pediatric ...

Hematopoietic stem cells (HSCs) are the precursors of all cells of the peripheral blood, and they usually reside in a quiescent state in the bone marrow. We discovered that interferon gamma (IFNγ) ...

Lupus is considered an 'interferonopathy' because almost all patients show elevated interferon activity in their blood and ...