For example, activated T helper type 1 lymphocytes secrete interferon (IFN)-γ, which has potent effects on osteoclastogenesis in vivo and in vitro. IFN-γ, however, is known to cause both bone ...

Interferon gamma (IFN-γ) is a cytokine that induces a series of immune responses against viruses and tumors. The pro-apoptotic, anti-tumor and anti-proliferative actions of the cells are ...

On the 50th anniversary of the discovery of interferon (IFN), we offer a perspective from more than 100,000 published papers, highlighting initial pivotal discoveries and more recent findings of ...

In particular, older adults showed an impaired ability to support TH1 immunity, with diminished early inflammatory responses, and lower levels of four key cytokines (CXCL10, IL-1RA, IFN-g ...