Of these epigenetically labile targets, the transposable elements and imprinted genes are particularly important. Transposable elements and metastable epialleles. Most regions of the adult ...

Using advanced stem cell engineering techniques, researchers from the Chinese Academy of Sciences and Sun Yat-sen University targeted 20 key imprinting genes. These are the genes that regulate how ...

Sexual reproduction in mammals is a complex process. It involves a balance between the genetic material of both parents. A crucial mechanism, called genetic imprinting, plays a key role in this ...

Some of our genes can be expressed or silenced depending on whether we inherited them from our mother or our father. The ...

Mammalian reproduction involves genomic imprinting, a process in which epigenetic modifications restrict the expression of certain genes to a single parental allele. The genes that are silenced or ...

In the new study, mice were created through genetic editing of mouse embryonic stem cells targeting a class of mammal-specific genes known as imprinted genes, of which there are about 200, the ...

The work has been reported in Cell Stem Cell. Gene imprinting refers to a process in which cells either express a gene from one parent, while the copy of that gene that is inherited from the other ...

Genomic imprinting is a mechanism that regulates gene expression based on parental origin, requiring every embryo to derive from a male gamete (sperm) and a female gamete (egg). "The unique ...

Until now, many similar attempts have resulted in unhealthy offspring. "The unique characteristics of imprinting genes have led scientists to believe that they are a fundamental barrier to ...

A team of scientists created a bi-paternal mouse through targeted imprinting gene edits in embryonic stem cells. This demonstrates the potential for overcoming barriers to unisexual mammalian ...