On the 50th anniversary of the discovery of interferon (IFN), we offer a perspective from more than 100,000 published papers, highlighting initial pivotal discoveries and more recent findings of ...
Rare genetic mutations that prevent infected cells from boosting the production of antiviral molecules known as interferons are responsible for ... opens in a new tab, a Howard Hughes Medical ...
A significant body of data implicates the type I interferon (IFN) pathway in the pathogenesis of autoimmune rheumatic diseases. In these disorders, a self-reinforcing cycle of IFN production can ...