Kaleido Scope1 小时
Key regulator that induces cancer-killing capacity in T cells under hypoxia is identified
The regulator HIF1α functions in a cancer-microenvironment that lacks oxygen, and it may be involved in resistance to immune ...
腾讯网26 天
γ-干扰素释放试验的结果解读：从固定阈值到边界范围的灵活应用
γ-干扰素释放试验（interferon-γreleaseassay，IGRA）是现代医学中用于检测结核分枝杆菌感染的主要工具之一，因其高特异性且不受卡介苗（BCG）接种 ...
Nature1 个月
Type I interferons: crucial participants in disease amplification in autoimmunity
The type I interferon (IFN) system constitutes a highly ... targeting type I IFNs are addressed. Type II IFN (IFN-γ) is quite distinct from types I and III IFN. Only natural killer (NK) cells ...
Nature1 年
Interferons at age 50: past, current and future impact on biomedicine
On the 50th anniversary of the discovery of interferon (IFN), we offer a perspective from more than 100,000 published papers, highlighting initial pivotal discoveries and more recent findings of ...
The New England Journal of Medicine1 天
Learning/CME
Infection with an atypical mycobacterium in an otherwise healthy child warrants investigation for abnormalities in the number and function of T cells, defects in interferon-γ signaling ...