This modification regulates the activity, localization, and function of proteins, ultimately influencing various cellular ...

It is no surprise then that academic labs and pharmaceutical companies are hot on the trail of understanding kinase function. Kinases impart their signal by transferring the γ-phosphate group ...

WNKs sense osmotic pressure by binding specific water molecules to the inactive dimeric configuration of WNK1 and WNK3, integrating signals with chloride inhibition as demonstrated by mutagenesis and ...

Northwestern Medicine scientists have uncovered new details about how the spinal column forms in developing vertebrates, ...

A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights ...