The polymorphic nature of KIRs and their ligands adds a layer of complexity to NK cell interactions with tumor cells. Moreover, other inhibitory receptors like CD94/NKG2A, PD-1, TIGIT, and TIM-3 ...

A review discussing the therapeutic potentials of NK cell biology has been published in the journal Frontiers of Medicine.

The polymorphic nature of KIRs and their ligands adds a layer of complexity to NK cell interactions with tumor cells. Moreover, other inhibitory receptors like CD94/NKG2A, PD-1, TIGIT, and TIM-3 ...

Overview of current approaches to improve effectiveness of adoptive transfer of NK cells by manipulation of the NK cell product, the host and the target. Human NK cells are a subset of peripheral ...

ILT: Immunoglobulin-like transcript; KIR: Killer cell immunoglobulin-like receptor; LIR: Leukocyte immunoglobulin-like receptor; MIC: MHC class I-like; NKR: Natural killer cell receptor; ULBP ...

Natural killer (NK) cells play an important role in the innate immune response to cancer and viral infections, and their ...