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Nature
7 年
The right team at the right time to go for a home run: tyrosine kinase activation by the TCR
by the coreceptors CD4 and CD8. But Lck was not the whole kinase story. Terri Kadlecek had been immunoprecipitating the ζ-chain from TCR-stimulated Jurkat cells and found an associated 70-kDa ...
11 个月
on MSN
Evolutionary conservation of CD4 and LAG-3 and their cytoplasmic tail motifs with opposing ...
This induces T cell activation by promoting the binding of the intracellular kinase LCK to the CD4 ... stretch inhibit the ...
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