In the original lentivirus vectors described by Naldini et al (Naldini et al., 1996a) (Naldini et al., 1996b) , the vector pCMVΔR8.2 supplies all but the HIV envelope in trans, the vector pMD.G is ...
Current lentiviral vector systems (the third generation) generate virus particles using four plasmids and a producer cell line. The rationale behind four plasmids is to enhance safety, as ...
The popularity of viral vector-based gene therapies and vaccines is rapidly ... Download this application note from Thermo Fisher Scientific to learn how scientists have used their lentiviral ...