Studies have found that the gene encoding Lgr5 (leucine-rich-repeat-containing G-protein-coupled receptor 5) is expressed in colon cancer cells and in ovarian and hepatocellular carcinomas.
What To Know: This payment aligns with their 2020 exclusive license agreement for BNC101, a monoclonal antibody targeting LGR5, a cancer stem cell antigen. Carina Biotech is developing an LGR5 ...
Netherlands-based clinical-stage biotech Merus on Saturday announced interim clinical data as of a July 5, 2024 data cutoff ...
2024年12月2日，Hans ...
引言胰腺是人体内一个复杂而重要的器官，承担着消化和内分泌的双重功能。然而，由于其组织构成的复杂性以及在实验室环境中长期维持功能性胰腺细胞的困难，针对胰腺的研究一直面临挑战。近年来，类器官（organoids）技术的发展为这一领域带来了革命性的突破。类 ...
For the most mature data set, the single arm cohort previously presented at AACR 2023, as of a July 5, 2024 data cutoff, for all 54 patients, the median DOR, PFS and OS were 6.7, 5.1, and 12.0 months, ...
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Petosemtamab 1500 mg monotherapy phase 2 interim data continues to demonstrate clinically meaningful activity in 2L+ HNSCC - Conference call on Saturday, Dec. 7 at 9:00 a.m. ET to discuss full data ...
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