N-methyl D-aspartate (NMDA) receptors are ligand-gated cation channels activated by glutamate, an excitatory neurotransmitter. These receptors are located mostly at excitatory synapses and ...

In contrast, TLRs 3, 7, 8, and 9 are situated in the membranes of endosomes and lysosomes; the extracellular domain of the receptor and its ligand-binding site project into the interior of these ...

Researchers developed SNIPRs, innovative receptors that sense soluble ligands, enabling precise therapeutic control in CAR ...

With its STRIKE (Selectively Targeting RNA Into KidnEy) platform, the company is using a proprietary approach to create ligand-RNA conjugate drugs designed for receptor-mediated update by specific ...

Aurigene Oncology Ltd. has divulged compounds acting as dual antagonists of adenosine receptor A2A (ADORA2A) and programmed cell death 1 ligand 1 (CD274; PD-L1) reported to be useful for the treatment ...

Chemistry, 2010, 53, 1357. “Benzimidazole derivatives as novel serotonin 5-HT 6 receptor antagonists. A computacional and mutagenesis study of ligand-receptor interaction”. Drugs of the Future 2009, ...

Royce & Associates LP lessened its holdings in shares of Ligand Pharmaceuticals Incorporated (NASDAQ:LGND – Free Report) by 45.1% in the 3rd quarter, Holdings Channel reports. The institutional ...