LAU-7b is a new chemical entity based on fenretinide, a small molecule drug that works against the SARS-CoV-2 virus in several ways, all related to modulating membrane lipids (Fig. 1). LAU-7b ...

2024 年 10 月 1 日，以北京大学基础医学院病原生物学系为第一完成单位，军事科学院军事医学研究院秦成峰研究员团队与北京大学鲁凤民 / 王麟研究团队合作在胃肠道肝病领域期刊 Gut 上发表题为 “ Establishment of ...

RNA enveloped viruses comprise several families belonging to plus and minus strand RNA viruses, such as retroviruses, flavoviruses and orthomyxoviruses. Viruses utilize cellular lipids during critical ...

RNA enveloped viruses comprise several families belonging to plus and minus strand RNA viruses, such as retroviruses, flavoviruses and orthomyxoviruses. Viruses utilize cellular lipids during critical ...

Nearly six months after lodging a similar complaint against Pfizer and BioNTech over the partners’ COVID shot Comirnaty, GSK ...

Researchers are developing a new generation of antiviral drugs that target the membranes of viruses instead of the surface proteins. These drugs, inspired by our immune system, show promise against ...

New insights into how the human immunodeficiency virus (HIV) curates and assembles its lipid envelope have been gleaned by RIKEN biologists. These findings into HIV biology could help to inform ...

However, the roles of SphK2 in the hepatic lipid metabolism of NAFLD have not been elucidated. Methods Wild-type (SphK2-Flox), hepatocyte-specific SphK2 knockout (SphK2-HKO) mice and SphK2 ...