In a mouse corneal angiogenesis assay, FGF-2 stimulates both lymphangiogenesis and angiogenesis. FGF-2 upregulates VEGF-C expression in vascular endothelial and perivascular cells. Anti-VEGFR-3 ...

When a tumour develops, it creates a structure around itself called the tumour stroma, within which blood and lymphatic vessels ensure nutritional and respiratory biological exchanges.

When a tumor develops, it creates a structure around itself called the tumor stroma, within which blood and lymphatic vessels ensure nutritional and respiratory biological exchanges. Lymphangiogenesis ...

In this illustrative study, we used MDA-MD-468LN and ΔVEGF-D/468LN cells to examine the role of VEGF-D expression by tumor cells on tumor-induced lymphangiogenesis in vivo. VEGF-D secretion (24 ...

We do biomedical research in vascular biology with a focus on lymphangiogenesis and the VEGF family of growth factors. Blood and lymphatic vessels play important roles in almost all major human ...

The functional lymphatic vessels transport inflammatory lymph-carrying inflammatory cells, catabolic factors and cytokines to the draining LNs and promote lymphangiogenesis, leading to an ...