Lymphoid tissues are organized structures that support immune responses. The bone marrow and thymus are primary lymphoid tissues and the sites of lymphocyte development. The lymph nodes ...

Background: Substantial studies reveal that tertiary lymphoid structure (TLS) correlate with prognosis and immunotherapy response in various types of cancers. However, the predictive value of TLS, the ...

AtLP are conditions in which it is not possible to differentiate between the benign and the malignant nature of a given lymphoid infiltrate. The descriptive term AtLP may be used as an interim ...

Discover important insights into the clonal evolution of blastic plasmacytoid dendritic cell neoplasm, a rare and aggressive ...

However, recent studies by Rodrigues et al. (Nature Immunology, 2018) and Dress et al. (Nature Immunology, 2019) have challenged this perspective, proposing that pDCs predominantly develop from ...

Additionally, the spatial organization of immune cells within the tumor microenvironment can be of major importance. For example, the presence of highly organized ectopic lymphoid structures, called ...

Objective To better understand the immune microenvironment of pancreatic ductal adenocarcinomas (PDACs), here we explored the relevance of T and B cell compartmentalisation into tertiary lymphoid ...

Background Tertiary Lymphoid Structures (TLSs) develop in non-lymphoid tissues at sites of chronic inflammation, including hepatocellular carcinoma (HCC). A favorable impact of TLSs on preventing ...

You will be able to get a quick price and instant permission to reuse the content in many different ways. Pulmonary lymphoid lesions encompass a spectrum of inflammatory and reactive lesions that are ...

Objective Type 2 innate lymphoid cells (ILC2s), a recently identified population of lymphoid cells lacking lineage-specific receptors, promote type 2 immunity and tissue remodelling. However, the ...

Hepatic reactive lymphoid hyperplasia is an uncommon benign condition, often found incidentally as a solitary liver lesion. The chronic inflammatory reaction associated with autoimmune conditions and ...

This important study provides solid in-vivo evidence that CCR4 regulates the early inflammatory response during atherosclerotic plaque formation. The authors propose that altered T-cell response plays ...