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谷氨酰胺代谢开关支持红细胞生成
一项由Lyu等人领导的最新研究揭示了红细胞生成过程中的一个关键代谢适应,即谷氨酰胺合成酶(GS)的活性增强。这项研究在小鼠骨髓红系前体细胞中进行,发现谷氨酰胺合成酶的活性增强有助于消耗血红素生成过程中积累的多余铵,防止细胞损伤。研究还 ...
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