Figure 1: MHC class II expression is reduced in HCMV-infected cells. Figure 2: US2 induces degradation of class II-α chains by proteasomes without a cytoplasmic intermediate and binds to class II ...

has unveiled groundbreaking research in Science Immunology that illustrates how human LAG-3 binds to MHC Class II molecules. This discovery lays a crucial foundation for developing new LAG-3 ...