That difference is actually a survival benefit: The combination of two individuals' different MHC (major histocompatibility locus) genes gives their offspring an advantage in beating back disease ...
An intracellular sensor that tracks the quality of so-called MHC-I molecules which aid the immune system in identifying and ...
The majority of highly polymorphic genes are related to immune functions and with over 100 alleles within a population, genes of the major histocompatibility complex (MHC) are the most polymorphic ...
Figure 1: Interference of MHC multimer staining with T-cell function in vitro. Figure 2: Interference of MHC multimer staining with T-cell function in vivo. Several factors must be considered in ...
The major histocompatibility complex (MHC) genes are involved in the immune system's response to tumor and infected cells and in generating an immune response. This book brings together basic aspects ...