老规矩,奇点糕开头先问大家一个问题:在激活CD8+T细胞抗肿瘤免疫应答时,有哪些细胞会起到重要作用呢?回答树突状细胞(DCs)是肯定没问题的,它们的抗原呈递功能确实广为人知,但各位要记住了,从今天开始DCs可就不是问题唯一的“正解”了。因为在今天的《 ...
CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...
The CD8-mediated binding can usually be blocked by inclusion of select CD8 monoclonal ... Prepare 2x staining cocktail containing all of your labeled reagents at the right titer. The suggested titer ...
Containing mutations in the MHC α3 domain that ablate CD8 binding; can be used to quantitate and to sort CD8-independent T cells ... Epitopes were previously identified in SARS and are 100 percent ...