Researchers have long known that there is a relationship between the cancer-associated gene MYC (pronounced "Mick") and ...

MYC/MYCN是髓母细胞瘤（MB）中最常见的癌基因扩增，也是其高危（HR）疾病的主要生物标志物。然而，尽管许多携带MYC（N）扩增肿瘤的患者对治疗有耐药性，但也有一些患者能够实现长期生存。因此，研究者对MYC（N）扩增型MB内的临床生物学异质性进行 ...

A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights ...

磷酸果糖激酶血小板型（PFKP）是糖酵解途径中的一个关键限速酶，它的异常表达通过改变多种生物学功能在多种人类癌症的发展中起着至关重要的作用。然而，PFKP在HNSCC中作用的确切分子机制尚未完全阐明。c-Myc是一个涉及细胞增殖、分化、上皮-间充质转 ...

Just over 25 years ago, MYC, the human homologue of a retroviral oncogene, was identified. Since that time, MYC research has been intense and the advances impressive. On reflection, it is ...

New York City Mayor Eric Adams exits the Manhattan federal courthouse on Thursday, Sept. 27, 2024, after pleading not guilty to federal bribery and corruption charges. (Josh Russell/Courthouse News ...