Meanwhile, in biopsies from patients with pain due to diabetic neuropathy (right), macrophages (red) surround degenerating nerve fibers (green). Advanced Search Home ...

Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.

Macrophages interact with T cells in order to bring about T cell activation in target organs, and are themselves activated by inflammatory messenger molecules (cytokines) produced by the T cells.

Meghan Morrissey wants to understand how macrophages measure, add and subtract all the signals they receive to calculate their response to a target. We use high resolution live imaging, synthetic ...

A discovery offers new hope in the battle against pulmonary fibrosis, a debilitating lung condition that progressively makes it harder for patients to breathe. Scientists have pinpointed proteins in ...

Researchers at Duke-NUS Medical School have identified YAP and TAZ proteins as key drivers of pulmonary fibrosis. Blocking ...

The $4.9 billion acquisition of Forty Seven by Gilead is an example of the explosive excitement and investment into macrophage-directed therapies, utilizing CD47 checkpoint blockades ...

Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...

A discovery at Duke-NUS Medical School offers new hope in the battle against pulmonary fibrosis, a debilitating lung condition that progressively makes it harder for patients to breathe. Scientists ...

Researchers have identified YAP and TAZ as crucial regulators of macrophage-mediated pulmonary inflammation and fibrosis, ...