This Research Topic is part of the Sub-molecular Mechanism of Genetic Epilepsy series: Sub-molecular Mechanism of Genetic Epilepsy, Volume I Protein is the essential functional molecule ...

over the past decade epilepsy researchers have increasingly discussed and promoted the concept of targeting underlying brain mechanisms of epileptogenesis and injury that cause epilepsy and its ...

Several comorbidities have been suggested to cause, precipitate, or worsen epilepsy, but the mechanisms behind many of these associations remain unknown. The conceptualisation of epilepsy as an index ...

The largest and most diverse study to date of epilepsy's genetic factors has revealed new potential targets for treatment, ...

The Laboratory of Epilepsy and Emotional Behavior, led by Vaishnav Krishnan, M.D., Ph.D., is devoted to advancing our knowledge of the basic neurobiological mechanisms that underlie the strong ...

Patients with PVNH often experience epilepsy due to ectopic neuronal discharges. Most cases of PVNH are associated with variations in filamin A (FLNA), which encodes an actin-binding protein. However, ...

In research aspect, he is devoted to the study of the pathogenesis of epilepsy and the mechanism of epilepsy resistance and have hosted four National Natural Science Foundation Projects. He published ...

It is reasonable to hypothesize that the same mechanisms that account for normal synaptic plasticity might also mediate pathophysiological changes in dendrites with epilepsy, but in a more extreme ...

No currently available anti-seizure drug uses this mechanism. The drug’s sponsor, Eisai, reported favorable results from a mainly European and Asian trial in 706 patients who received 2, 4 or 8 mg of ...

A recent Acta Neuropathologica study identifies shared mechanisms between epilepsy and Alzheimer’s disease (AD) using proteomics. Study: Similar brain proteomic signatures in Alzheimer’s ...