Translating mouse models into clinical therapies has never been easy. Immunotherapies for cancer also have to contend with an approval process designed for testing drugs. It may be necessary to ...

Our laboratory is interested in the use of mouse models of prostate cancer to explore the pathogenesis of prostate cancer and its response to treatment. We have used the SV-40 based TRAMP model of ...

However, few studies have experimentally addressed the role of mtDNA levels in tumor progression. LUAD was induced by ...