UCLA scientists have identified a potential new strategy for treating glioblastoma, the deadliest form of brain cancer, by ...

“It’s not clear whether microglia are…facilitating the progression of these diseases or trying to block the progression…to save the neuron,” said Zurzolo. Zurzolo’s team first determined if functional ...

UOW researcher awarded more than $700k from Race Against Dementia to investigate new approaches to targeting devastating disease A major ...

UCLA scientists have identified a potential new strategy for treating glioblastoma, the deadliest form of brain cancer, by ...

Others have produced little spheres of human neural tissue by combining neurons, astrocytes, and microglia, all derived from induced pluripotent stem cells. Neurons in this system were more active ...

Electron micrographs show typical microglia in the prefrontal cortex of a 92-year-old healthy female (left) and dark microglia a 91-year-old female patient with Alzheimer’s disease (right).

The study, published in the journal Neuron, highlights microglia, the brain's primary immune cells, as central players in both the protective and harmful responses associated with the disease.

The researchers noted that these effects did not alter the taste circuit entirely, as a third nerve in the system was not affected by the diet. Since microglia help prune excess neuron terminals, the ...

ApoE3Ch Curbs Tau Toxicity. In neurons (blue bottom), ApoE3Ch binds tightly to tau and prevents its fragmentation. In the extracellular space it prevents tau uptake into neurons and microglia.