New research reveals the pivotal role of a mitochondrion-localized protein, PtoRFL30, in the wood formation of poplar trees.

We are driven to understand the signals regulating tissue-specific autophagy signalling in mammalian health and disease. Understanding the physiological regulation and significance of selective ...

Moreover, as a protein localized in the mitochondria, is MAVS linked to mitochondrial homeostasis, which in turn regulates stem cell function? Answering these questions will deepen our ...

Model for mitochondrial homeostasis mediated by PtoRFL30 during wood formation in poplar. During wood formation, nuclear-encoded protein PtoRFL30 targets mitochondria, and affects mitochondrial ...

In conclusion, by identifying PEBP1 as an amplifier of mitochondrial stress signals, our study provides new insights into cytoplasmic mechanisms which ensure appropriate responses to acute ...

Oleuropein enhances mitochondrial calcium uptake, reversing age-related declines in muscle function and energy metabolism, ...

Under normal conditions, microglia maintain neuronal homeostasis and clear metabolic byproducts. However, in AD, mitochondrial dysfunction leads to abnormal microglial activity, resulting in ...

More recently, Dr Raimondi joined the William Harvey Research Institute (WHRI) to investigate the interplay of NRP1 signalling, mitochondria homeostasis and EC metabolism in endothelial cell ...