A harmless, modified adenovirus carries the DNA in their vaccine. “We had used this to make many different vaccines in the past,” Gilbert said, some of which were already in phase 1 clinical ...

In 2012, researchers at the University of Oxford created ChAdOx1, a virus vector vaccine based on a modified simian adenovirus. The researchers chose a simian adenovirus because “if you use a ...

This cassette is then transferred to the adenovirus vector plasmid (pAdeno X, Clontech Laboratories or pAd5F35, The Journal of Gene Medicine Volume 6, Issue 6 , Pages 631 - 641). The adenovirus vector ...

Fintel reports that on February 19, 2025, Canaccord Genuity initiated coverage of Candel Therapeutics (NasdaqGM:CADL) with a ...

These viruses are modified to remove their ability to cause disease while retaining their capability to enter cells and deliver the desired genetic payload. Example for viral gene therapy using an ...

Candel has established two oncolytic viral immunotherapy platforms based on novel, genetically modified adenovirus and herpes simplex virus (HSV) constructs. CAN-2409 is the lead product candidate ...