I formulated the missing-self hypothesis for natural killer (NK) cell recognition in the autumn of 1981, while writing the last chapter of my doctoral thesis. In 1975, I had joined the Department ...

Physical exercise plays an important role in controlling disease, including cancer, due to its effect on the human body’s ...

NK cells recognize cell-bound antibodies via CD16A (FcγRIIIA) to mediate antibody-dependent cellular cytotoxicity (ADCC). Potentiating therapeutic mAb-mediated CD16 activation of NK cells is an ...

Source: Sino Biological Inc. To mediate antibody-dependent cellular cytotoxicity (ADCC), NK cells recognize cell-bound antibodies via CD16A (FcγRIIIA). A new area of cancer immunotherapy is ...

CAR-NK therapy involves modifying NK cells using ... “But importantly, you also activate memory T cells. With this, if you can activate the immune system, then, once you’ve stopped the ...

a subset of NK cells bearing the activating Ly49H receptor, which specifically binds the viral glycoprotein m157, can proliferate 100-1000 fold in lymphoid and non-lymphoid organs following mouse ...

NK cells and gamma delta (γδ) T-cells – are activated to directly attack and kill tumor cells upon contact, while critically shaping the overall tumor microenvironment to be more permissive to ...

Severe infection with Covid-19 has been found to produce a powerful cancer-fighting cell that can shrink tumors.

For solid tumors and hematological malignancies, CAR-NK cell treatment is a novel kind of cancer immunotherapy. CAR-NK cells work by killing cancer cells in a CAR-dependent way. CAR-NK cells and ...