In multicellular organisms, the total number of cells is a balance between the cell-generating effects of mitosis and cell death that is induced through apoptosis. A disruption of this delicate ...
Intracellular checkpoint molecules like BIM, which mediates apoptosis in NK cells, can be targeted to enhance antitumor responses. The absence of BIM in NK cells has been shown to increase their ...
natural killer (NK) cell product candidate that incorporates multiple novel synthetic controls of cell function designed to target and deplete pathogenic immune cells, and is the Company’s first ...