We found that interleukin 4 receptor (IL-4R) knockout and downstream ... Loss of natural killer T cells (NKT cells) in CD1 knockout mice resulted in decreased IL-13 production and resistance ...

Yang及其同事此前报道了一种临床引导培养方法，通过改造人类造血干细胞和祖细胞来产生异体CAR-NKT细胞。作为潜在的应用，本文作者描述了异体cd33靶向CAR-NKT细胞的设计和特性，在骨髓常驻髓系恶性肿瘤的临床前模型中显示出抗肿瘤活性。 新型免疫细胞疗法 ...

Next, the authors showed that the influx of NKT cells to the NALT and CLNs following nasal vaccination with α-GalCer was mediated by CXC-chemokine receptor 6 (CXCR6) expressed by NKT cells ...