I formulated the missing-self hypothesis for natural killer (NK) cell recognition in the autumn of 1981, while writing the last chapter of my doctoral thesis. In 1975, I had joined the Department ...
NK细胞与其它免疫细胞的沟通非常紧密,它们能够迅速应对衰老细胞。科学家们已经发现了一些特定的生物标志物,比如uPAR,它在衰老细胞中表达量上升,并与衰老的进程相关。这些发现提供了评估NK细胞疗法效果的科学依据。
Clinical relevance: Receptor engineering has significantly advanced NK cell-based cancer immunotherapies. As technical hurdles are overcome, these innovative treatments are poised to revolutionize ...
A review discussing the therapeutic potentials of NK cell biology has been published in the journal Frontiers of Medicine.
Creating cancer therapies based around natural killer cells could offer similar levels of efficacy to CAR-T therapies, but at around one hundredth of the cost. Researchers at MD Anderson Cancer ...
Natural killer (NK) cells play an important role in the innate immune response to cancer and viral infections, and their ...
NKGen and its partners can begin to commercialize troculeucel in Korea, Japan and other markets where natural-killer (“NK”) cell therapy is already legal. NKGen proposal included up to $18 million in ...
The firm plans to put the proceeds toward further developing its cell therapy in CD33- or FLT3-expressing AML and for other R&D activities.