I formulated the missing-self hypothesis for natural killer (NK ... what was known about NK cell specificity and compare it to T cell specificity, preferably in one sentence.
In 2010, a milestone was achieved when the first patient with cancer was treated with CAR-T-cell therapy ... Rezvani decided to add the CAR gene to natural killer (NK) cells.
Studying the basics of natural killer (NK ... Additionally, engineering NK cells with T-cell receptors has expanded the range of targetable peptides by allowing recognition of intracellular ...
T-cell engagers, however, can cause serious toxicities, according to the release, while recent research suggests treatments based on natural killer cells may be safer. Innate’s antibody binds to ...
Arovella Therapeutics Ltd. is heading toward the clinic with its lead product, ALA-101, which consists of a chimeric antigen receptor (CAR) targeting CD19 and invariant natural killer T (iNKT) cells.