A cell in yellow is shown dying by necroptosis, a process requiring the protein MLKL Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert!
Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including ...
cells, especially M4 and M5 subtypes, produce TNF and show basal level activation of RIP1/RIP3/MLKL signaling, yet do not undergo necroptosis. TNF, through RIP1/RIP3 signaling, prevents ...
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