What about the rest of the cases of CHD? Noncoding DNA elements have long been thought to play a role in CHD, but few variants have been pinned down as causative. New work from the lab of ...

Most of these variants map to noncoding genomic regions ... Parking a giant CRISPR repressor on DNA is helpful for discovering causal variants, but it is not realistic in a biological sense. STING-seq ...

Much of the "junk" DNA in Drosophila shows signs of either negative or positive selection, according to a study in this week's Nature. An analysis by Peter Andolfatto of the University of California, ...

An artificial-intelligence network trained on a vast trove of sequence data is a step towards designing completely new ...

Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions ...

Humans have appreciated the beauty of flowers for centuries. Yet, flowers aren't just aesthetically pleasing. They also play ...

Swiss start-up Haya Therapeutics has formed a partnership with Eli Lilly – worth up to $1 billion – to look for new therapies for obesity in non-coding DNA. The biotech focuses on trawling the ...

Now, using CRISPR gene editing, Cold Spring Harbor Laboratory (CSHL) Professor and HHMI Investigator Zachary Lippman and his ...

The involvement of noncoding mRNAs in many regulatory processes ... that an "RNA world" may have preceded the evolution of DNA and proteins (Gilbert, 1986). Small interfering RNAs (siRNAs ...