Legius syndrome was discovered in the past several years. It is characterized by having multiple cafe-au-lait spots, and sometime skin fold freckles, indistinguishable from those that occur in NF1. It ...

Incidentally, people with NF1 have a 15-fold increased risk of developing optic nerve glioma compared to the general ...

Patients with multiple CALMs w/wo skinfold freckling and no other typical NF1 associated features (Lisch nodules, bone abnormalities, neurofibromas, optic pathway gliomas). The DNA-based ...

Neurofibromatosis is a rare disease with ... with their hearing and also eyesight if they are associated with optic glioma ...