PDGF-B secreted from skeletal muscle cells enhances not only cell proliferation but also muscle hypertrophy accompanied by contractile function.

Platelet-derived growth factor subunit B (PDGFB), also known as FLJ12858, PDGF2, SIS, SSV, and c-sis, belongs to the PDGF family. It can form either a homodimer (PDGF-BB) or a heterodimer with the ...