然而，克服紫杉醇耐药性仍是一个未解决的问题。 2月6日，中山大学研究团队在期刊《Clinical And Translational Medicine》上发表了研究论文，题为“RNF31 induces paclitaxel resistance by sustaining ALYREF cytoplasmic–nuclear shuttling in human triple-negative ...

The research team made the discovery whilst exploring the possible mechanisms behind resistance to chemotherapy drugs like Paclitaxel, often used to treat breast and colon cancer. Dr Andrew Gilmore, ...

Th e GINECO trial explored the combination of trastuzumab with paclitaxel and carboplatin in patients with resistant AOC (< 6 months) and HER2 gene amplification. Patients and Methods: A total of ...

Drug resistance has become a significant challenge in clinical cancer treatment. One specific modification, microtubule acetylation, is catalyzed by an enzyme called tubulin acetyltransferase and has ...