All antibiotics can cause drug rashes — as can antiseizure and antigout medications and even over-the-counter medications like NSAIDs. And while some patients have severe reactions, the majority ...
Gonçalo and colleagues [16] patch-tested 66 patients (aged 12 to 83 years) with a history of a maculopapular rash to antibiotics (58%), antiepileptics (25%), allopurinol (11%), or other drugs (6%).
The rash was not responsive to topical or oral corticosteroids and worsened after infliximab infusions and after subsequent administration of a second anti-TNF drug, adalimumab. Investigations.
or maculopapular rashes from ampicillin, amoxicillin, or penicillin over time. Four patients showed an increased severity of reactions at 18 months, 4 years, 6.5 years, and 7.5 years later ...